Azido-PEG1

Modify Date: 2024-01-02 10:58:09

Azido-PEG1 Structure
Azido-PEG1 structure
 Common Name Azido-PEG1
CAS Number 1517-05-1 Molecular Weight 325.795
Density 1.3±0.1 g/cm3 Boiling Point 411.7±45.0 °C at 760 mmHg
Molecular Formula C17H16ClN5 Melting Point N/A
MSDS N/A Flash Point 202.8±28.7 °C

 Use of Azido-PEG1


Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Azidoethanol
Synonym More Synonyms

 Azido-PEG1 Biological Activity

Description Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 411.7±45.0 °C at 760 mmHg
Molecular Formula C17H16ClN5
Molecular Weight 325.795
Flash Point 202.8±28.7 °C
Exact Mass 325.109436
PSA 69.98000
LogP 5.39
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.698

 Safety Information

HS Code 2929909090

 Customs

HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

4-Chloro-6-[2-(diphenylmethyl)hydrazino]-5-pyrimidinamine
5-Pyrimidinamine, 4-chloro-6-[2-(diphenylmethyl)hydrazinyl]-
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4-((1-(4-cyanobenzyl)-2,4-dioxo-1,2-dihydrothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)-N-pentylcyclohexanecarboxamide
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N-benzyl-4-((1-benzyl-2,4-dioxo-1,2-dihydrothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)cyclohexanecarboxamide
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N-(2-furylmethyl)-4-{[1-(2-methylbenzyl)-2,4-dioxo-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl]methyl}cyclohexanecarboxamide
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N-butyl-4-((1-(2-chlorobenzyl)-2,4-dioxo-1,2-dihydrothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)cyclohexanecarboxamide
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N-butyl-4-((1-(4-chlorobenzyl)-2,4-dioxo-1,2-dihydrothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)cyclohexanecarboxamide
932554-07-9
N-butyl-4-((1-(3-chlorobenzyl)-2,4-dioxo-1,2-dihydrothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)cyclohexanecarboxamide
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N-butyl-4-((1-(2-fluorobenzyl)-2,4-dioxo-1,2-dihydrothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)cyclohexanecarboxamide
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Chemsrc provides Azido-PEG1(CAS#:1517-05-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Azido-PEG1 are included as well.>> amp version: Azido-PEG1

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