Azido-PEG1-Boc

Modify Date: 2024-01-07 03:13:19

Azido-PEG1-Boc Structure
Azido-PEG1-Boc structure
Common Name Azido-PEG1-Boc
CAS Number 1374658-85-1 Molecular Weight 215.250
Density N/A Boiling Point N/A
Molecular Formula C9H17N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG1-Boc


Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG1-t-butyl ester
Synonym More Synonyms

 Azido-PEG1-Boc Biological Activity

Description Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H17N3O3
Molecular Weight 215.250
Exact Mass 215.126984
LogP 1.70

 Synonyms

MFCD22201524
Propanoic acid, 3-(2-azidoethoxy)-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 3-(2-azidoethoxy)propanoate