Azido-PEG1-amine

Modify Date: 2024-01-15 08:26:05

Azido-PEG1-amine Structure
Azido-PEG1-amine structure
Common Name Azido-PEG1-amine
CAS Number 464190-91-8 Molecular Weight 130.14800
Density N/A Boiling Point N/A
Molecular Formula C4H10N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG1-amine


Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-azidoethoxy)ethanamine
Synonym More Synonyms

 Azido-PEG1-amine Biological Activity

Description Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C4H10N4O
Molecular Weight 130.14800
Exact Mass 130.08500
PSA 85.00000
LogP 0.42506

 Synonyms

N3-PEG1-CH2CH2NH2
N3-PEG2-NH2
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