1807505-32-3

1807505-32-3 structure

Name: Azido-PEG1-PFP ester
Chemical Name: Azido-PEG1-PFP ester
CAS Number: 1807505-32-3
Molecular Formula: C₁₁H₈F₅N₃O₃
Molecular Weight: 325.191
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-10 01:44:34
Modify Date: 2024-03-11 19:18:54
Azido-PEG1-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG1-PFP ester
Synonyms	Pentafluorophenyl 3-(2-azidoethoxy)propanoate MFCD26793775 Propanoic acid, 3-(2-azidoethoxy)-, 2,3,4,5,6-pentafluorophenyl ester

Description	Azido-PEG1-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562