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464190-91-8

464190-91-8 structure
464190-91-8 structure
  • Name: Azido-PEG1-amine
  • Chemical Name: 2-(2-azidoethoxy)ethanamine
  • CAS Number: 464190-91-8
  • Molecular Formula: C4H10N4O
  • Molecular Weight: 130.14800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-17 17:56:23
  • Modify Date: 2024-01-15 08:26:05
  • Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-(2-azidoethoxy)ethanamine
Synonyms N3-PEG1-CH2CH2NH2
N3-PEG2-NH2
Description Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C4H10N4O
Molecular Weight 130.14800
Exact Mass 130.08500
PSA 85.00000
LogP 0.42506