1374658-85-1

1374658-85-1 structure

Name: Azido-PEG1-Boc
Chemical Name: Azido-PEG1-t-butyl ester
CAS Number: 1374658-85-1
Molecular Formula: C₉H₁₇N₃O₃
Molecular Weight: 215.250
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-14 14:52:55
Modify Date: 2024-01-07 03:13:19
Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG1-t-butyl ester
Synonyms	MFCD22201524 Propanoic acid, 3-(2-azidoethoxy)-, 1,1-dimethylethyl ester 2-Methyl-2-propanyl 3-(2-azidoethoxy)propanoate

Description	Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562