Mal-amido-PEG8-TFP ester

Modify Date: 2024-01-14 17:25:55

Mal-amido-PEG8-TFP ester Structure
Mal-amido-PEG8-TFP ester structure
Common Name Mal-amido-PEG8-TFP ester
CAS Number 1924596-31-5 Molecular Weight 740.69
Density N/A Boiling Point N/A
Molecular Formula C32H44F4N2O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-amido-PEG8-TFP ester


Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-amido-PEG8-TFP ester
Synonym More Synonyms

 Mal-amido-PEG8-TFP ester Biological Activity

Description Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C32H44F4N2O13
Molecular Weight 740.69

 Synonyms

MAL-AMIDO-PEG8-TFP ESTER
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