756525-93-6
756525-93-6 structure
- Name: Mal-amido-PEG8-NHS ester
- Chemical Name: Mal-PEG8-NHS
- CAS Number: 756525-93-6
- Molecular Formula: C30H47N3O15
- Molecular Weight: 689.70500
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-01-04 20:03:24
- Modify Date: 2024-04-05 11:45:56
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Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Mal-PEG8-NHS |
|---|---|
| Synonyms |
α-Maleimidopropionyl-ω-succinimidyl-8(ethylene glycol)
succinimidyl[(N-maleimidopropionamido)octaethyleneglycol]ester Alpha-Maleimidopropionyl-ω-succinimidyl-8(ethylene glycol) [3-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-propionylamino]-ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-propionic acid-2,5-dioxo-pyrrolidin-1-yl ester Maleimide-PEG8-NHS Ester |
| Description | Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C30H47N3O15 |
|---|---|
| Molecular Weight | 689.70500 |
| Exact Mass | 689.30100 |
| PSA | 204.00000 |
| Storage condition | 2-8°C |
| RIDADR | NONH for all modes of transport |
|---|