Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Human enteropeptidase-IN-1

Human enteropeptidase-IN-1 (compound 6b) is a highly potent, orally active and low systemic exposure enteropeptidase inhibitor. Human enteropeptidase-IN-1 boosts the increase in fecal protein output, and exhibits potent body weight loss in diet-induced obese (DIO) rat model. Human enteropeptidase-IN-1 can be used for anti-obesity research[1].

  • CAS Number: 1802891-23-1
  • MF: C20H18N4O7
  • MW: 426.38
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HKPerox-1

HKPerox-1 is a yellow-emitting fluorescent probe with excellent selectivity and sensitivity toward H2O2. HKPerox-1 can be used for molecular imaging of endogenous H2O2 in living cells[1].

  • CAS Number: 2240163-05-5
  • MF: C40H30N2O11
  • MW: 714.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Metaphit

Metaphit is a specific PCPantagonist and site-directed acylating agent of the [3H]phencyclidine binding site in rat brain homogenates[1]. Metaphit prevents PCP-induced locomotor behavior through presynaptic mechanisms[2].

  • CAS Number: 96316-00-6
  • MF: C18H24N2S
  • MW: 300.46
  • Catalog: Neurological Disease
  • Density: 1.12g/cm3
  • Boiling Point: 433.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 216.1ºC

Ethyl linoleate-13C18

Ethyl linoleate-13C18 (Linoleic Acid-13C18 ethyl ester) is the 13C labeled Ethyl linoleate. Ethyl linoleate inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators[1].

  • CAS Number: 202114-63-4
  • MF: C213C18H36O2
  • MW: 326.366
  • Catalog: Cardiovascular Disease
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Malabaricone A

Malabaricone Ais a natural product isolated fromM. malabarica[1].

  • CAS Number: 63335-23-9
  • MF: C21H26O3
  • MW: 326.42900
  • Catalog: Others
  • Density: 1.11g/cm3
  • Boiling Point: 488.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 263.1ºC

ciraparantag

Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]

  • CAS Number: 1438492-26-2
  • MF: C22H48N12O2
  • MW: 512.69600
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-(3-Methoxyphenyl)-4-methyl-2-(2-morpholinoethyl)pyridazin-3(2H)-one hydrochloride

6-(3-Methoxyphenyl)-4-methyl-2-(2-morpholinoethyl)pyridazin-3(2H)-one hydrochloride is a methionine adenosyltransferase 2A (MAT2A) inhibitor.

  • CAS Number: 13299-99-5
  • MF: C18H24ClN3O3
  • MW: 365.85400
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium 4-aminobenzenesulfonate

Sodium Sulphanilate is a biochemical indice of inflammation-associated acute-phase response[1].

  • CAS Number: 515-74-2
  • MF: C6H6NNaO3S
  • MW: 195.171
  • Catalog: Inflammation/Immunology
  • Density: 1.512 g/cm3
  • Boiling Point: N/A
  • Melting Point: 288ºC
  • Flash Point: N/A

Acetoxyvalerenic acid

Acetoxyvalerenic acid is a natural compound that could be found in valerian[1].

  • CAS Number: 84638-55-1
  • MF: C17H24O4
  • MW: 292.37000
  • Catalog: Neurological Disease
  • Density: 1.31 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran

(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical[1].

  • CAS Number: 128443-60-7
  • MF: C32H40O13
  • MW: 632.65
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DAF-FM DA

DAF-FM DA is a reagent to detect and quantify low concentrations of nitric oxide (NO); DAF-FM fluorescence can be detected by any instrument that can detect fluorescein, including flow cytometers, microscopes, fluorescent microplate readers and fluorometers.

  • CAS Number: 254109-22-3
  • MF: C25H18F2N2O7
  • MW: 496.41600
  • Catalog: Dye Reagents
  • Density: 1.56±0.1 g/cm3(Predicted)
  • Boiling Point: 695.7±55.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

DL-Arginine

DL-Arginine is used in physicochemical analysis of amino acid complexation dynamics and crystal structure formations.

  • CAS Number: 7200-25-1
  • MF: C6H14N4O2
  • MW: 174.201
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 367.6±52.0 °C at 760 mmHg
  • Melting Point: 228-232ºC
  • Flash Point: 176.1±30.7 °C

H-Leu-Asp-OH

H-Leu-Asp-OH is a biologically active peptide.

  • CAS Number: 32949-40-9
  • MF: C10H18N2O5
  • MW: 246.26000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AP-C4

AP-C4 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 5.2. AP-C3 does not inhibit cGKII-dependent anion secretion[1].

  • CAS Number: 682794-85-0
  • MF: C22H20N4O2
  • MW: 372.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phe-Arg-Arg-Gly

Phe-Arg-Arg-Gly is a polypeptide that can be used for agent coupling[1].

  • CAS Number: 642080-61-3
  • MF: C23H38N10O5
  • MW: 534.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N,N-Dimethylglycine hydrochloride

N,N-Dimethylglycine hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 2491-06-7
  • MF: C4H10ClNO2
  • MW: 139.581
  • Catalog: Others
  • Density: 1.069g/cm3
  • Boiling Point: 175.2ºC at 760 mmHg
  • Melting Point: 189-194 °C(lit.)
  • Flash Point: 59.8ºC

(3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate

Monomethyl auristatin E intermediate-13 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

  • CAS Number: 870640-64-5
  • MF: C21H35NO3
  • MW: 349.508
  • Catalog: Cancer
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 426.3±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.6±25.9 °C

FKK

FKK is an indazole derivative and also a novel bronchodilator.

  • CAS Number: 78299-79-3
  • MF: C17H17BrN2
  • MW: 329.23
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Alendronate sodium

Alendronate (sodium hydrate) is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM.

  • CAS Number: 121268-17-5
  • MF: C4H18NNaO10P2
  • MW: 325.124
  • Catalog: Cancer
  • Density: 1.857g/cm3
  • Boiling Point: 616.7ºC at 760 mmHg
  • Melting Point: 245°C
  • Flash Point: 326.7ºC

11-Hydroxyhumantenine

11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans[1].

  • CAS Number: 122590-04-9
  • MF: C21H26N2O4
  • MW: 370.44
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 536.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 278.4±32.9 °C

Araliadiol

Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cells growth with an IC50 value of 6.41 µg/mL[1].

  • CAS Number: 1354638-93-9
  • MF: C15H20O2
  • MW: 232.318
  • Catalog: Cancer
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 381.2±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 176.1±22.5 °C

6-Chloro-L-tryptophan

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ[1].

  • CAS Number: 33468-35-8
  • MF: C11H11ClN2O2
  • MW: 238.670
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 476.9±45.0 °C at 760 mmHg
  • Melting Point: 244-246ºC
  • Flash Point: 242.2±28.7 °C

Substance P-methyl ester

Substance P, [Met-OMet11] is a selective SP-P agonist. Substance P, [Met-OMet11] also is an active peptide. Substance P, [Met-OMet11] can be used for various biochemical studies[1][2].

  • CAS Number: 76260-78-1
  • MF: C64H99N17O14S
  • MW: 1362.64000
  • Catalog: Others
  • Density: 1.41g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

salicyl alcohol

Salicyl alcohol is an intermediate for medicine, perfume, pesticide.

  • CAS Number: 90-01-7
  • MF: C7H8O2
  • MW: 124.137
  • Catalog: MNK
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 238.6±7.0 °C at 760 mmHg
  • Melting Point: 83-85 °C(lit.)
  • Flash Point: 115.2±12.8 °C

2,3,5-Trimethyl-1,4-benzenediol

Trimethylhydroquinone is a key intermediate for the synthesis of Vitamin E or other trimethylhydroquinone derivatives with antioxidative effects[1].

  • CAS Number: 700-13-0
  • MF: C9H12O2
  • MW: 152.190
  • Catalog: SARS-CoV
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 298.3±35.0 °C at 760 mmHg
  • Melting Point: 169-172 °C(lit.)
  • Flash Point: 146.3±20.5 °C

ATX inhibitor 17

ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].

  • CAS Number: 2750152-64-6
  • MF: C29H29F5N8S
  • MW: 616.65
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DEAE-Sephadex A 25

DEAE-Sephadex A 25 is a weak anion exchanger[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Desmethylobtusin

1-Desmethylobtusin is an anthraquinone compound can be isolated from Cassia obtusifolia L[1].

  • CAS Number: 90985-57-2
  • MF: C17H14O7
  • MW: 330.29
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tri-p-tolylamine-N15

Tri-p-tolylamine-15N is the deuterium labeled Tri-p-tolylamine[1].

  • CAS Number: 311761-87-2
  • MF: C21H2115N
  • MW: 288.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotinyl-α-CGRP (mouse, rat)

Biotinyl-α-CGRP (mouse, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 1816258-61-3
  • MF: C172H278N52O54S3
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A