ATX inhibitor 17

Modify Date: 2025-08-27 09:03:03

ATX inhibitor 17 Structure
ATX inhibitor 17 structure
Common Name ATX inhibitor 17
CAS Number 2750152-64-6 Molecular Weight 616.65
Density N/A Boiling Point N/A
Molecular Formula C29H29F5N8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ATX inhibitor 17


ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].

 Names

Name ATX inhibitor 17

 ATX inhibitor 17 Biological Activity

Description ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].
Related Catalog
Target

IC50: 0.019 µM (ATX)[1]

In Vitro ATX inhibitor 17 (compound 25a) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1]. Cell Cytotoxicity Assay[1] Cell Line: MCF7, MDA-MB-231, A549, H2228 cells Concentration: 0-15 µM Incubation Time: 72 h Result: Showed excellent antiproliferative effects with IC50s of 1.01, 0.79, 13.40, >15 µM for MCF7, MDA-MB-231, A549, H2228 cells, respectively.
References

[1]. Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456.

 Chemical & Physical Properties

Molecular Formula C29H29F5N8S
Molecular Weight 616.65
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