1438492-26-2

1438492-26-2 structure

Name: ciraparantag
Chemical Name: di-arginine piperazine
CAS Number: 1438492-26-2
Molecular Formula: C₂₂H₄₈N₁₂O₂
Molecular Weight: 512.69600
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-12-28 09:49:45
Modify Date: 2025-08-27 21:55:58
Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]

Name	di-arginine piperazine
Synonyms	2-amino-5-guanidino-pentanoic acid (3'-{4-[3-(2-amino-5-guanidino-pentanoylamino)-propyl]-piperazin-1-yl}-propyl)-amide ciraparantag (2S,2'S)-N,N'-(1,4-Piperazinediyldi-3,1-propanediyl)bis[2-amino-5-[(aminoiminomethyl)amino]pentanamide] PER977

Description	Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease
References	[1]. Arundhati Das et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol, 2015, 4: 25. [2]. Tiffany Y Hu et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag, 2016, 12: 35-44.