ciraparantag

Modify Date: 2025-08-27 21:55:58

ciraparantag Structure
ciraparantag structure
Common Name ciraparantag
CAS Number 1438492-26-2 Molecular Weight 512.69600
Density N/A Boiling Point N/A
Molecular Formula C22H48N12O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ciraparantag


Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]

 Names

Name di-arginine piperazine
Synonym More Synonyms

 ciraparantag Biological Activity

Description Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants except VKAs and agratroban. [1][2]
Related Catalog
References

[1]. Arundhati Das et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol, 2015, 4: 25.

[2]. Tiffany Y Hu et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag, 2016, 12: 35-44.

 Chemical & Physical Properties

Molecular Formula C22H48N12O2
Molecular Weight 512.69600
Exact Mass 512.40200
PSA 240.52000
LogP 1.23780
InChIKey HRDUUSCYRPOMSO-ROUUACIJSA-N
SMILES NC(N)=NCCCC(N)C(=O)NCCCN1CCN(CCCNC(=O)C(N)CCCN=C(N)N)CC1
Storage condition 2-8℃

 Synonyms

2-amino-5-guanidino-pentanoic acid (3'-{4-[3-(2-amino-5-guanidino-pentanoylamino)-propyl]-piperazin-1-yl}-propyl)-amide
ciraparantag
(2S,2'S)-N,N'-(1,4-Piperazinediyldi-3,1-propanediyl)bis[2-amino-5-[(aminoiminomethyl)amino]pentanamide]
PER977
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