1438492-27-3
1438492-27-3 structure
- Name: Ciraparantag TFA
- Chemical Name: Ciraparantag TFA
- CAS Number: 1438492-27-3
- Molecular Formula: C26H50F6N12O6
- Molecular Weight: 740.74
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-01-23 15:32:51
- Modify Date: 2024-01-21 11:25:38
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Ciraparantag TFA is a thrombin and factor Xa inhibitor. Ciraparantag TFA is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban[1][2][3][4].
| Name | Ciraparantag TFA |
|---|
| Description | Ciraparantag TFA is a thrombin and factor Xa inhibitor. Ciraparantag TFA is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban[1][2][3][4]. |
|---|---|
| Related Catalog | |
| Target |
thrombin, factor Xa[1] |
| In Vitro | Ciraparantag TFA is a small-molecule antidote for unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), and certain direct oral anticoagulants (DOACs)[2]. Ciraparantag TFA is a small synthetic and cationic molecule that binds direct Xa inhibitors, direct thrombin inhibitors, and unfractionated and low molecular weight heparin (LMWH) through non-covalent hydrogen bonds and charge–charge interactions[3]. |
| References |
| Molecular Formula | C26H50F6N12O6 |
|---|---|
| Molecular Weight | 740.74 |