Human enteropeptidase-IN-1
Modify Date: 2024-01-28 11:12:42
Human enteropeptidase-IN-1 structure
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Common Name | Human enteropeptidase-IN-1 | ||
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| CAS Number | 1802891-23-1 | Molecular Weight | 426.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H18N4O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Human enteropeptidase-IN-1Human enteropeptidase-IN-1 (compound 6b) is a highly potent, orally active and low systemic exposure enteropeptidase inhibitor. Human enteropeptidase-IN-1 boosts the increase in fecal protein output, and exhibits potent body weight loss in diet-induced obese (DIO) rat model. Human enteropeptidase-IN-1 can be used for anti-obesity research[1]. |
| Name | Human enteropeptidase-IN-1 |
|---|
| Description | Human enteropeptidase-IN-1 (compound 6b) is a highly potent, orally active and low systemic exposure enteropeptidase inhibitor. Human enteropeptidase-IN-1 boosts the increase in fecal protein output, and exhibits potent body weight loss in diet-induced obese (DIO) rat model. Human enteropeptidase-IN-1 can be used for anti-obesity research[1]. |
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| Related Catalog | |
| Target |
IC50(initial): 20 nM (enteropeptidase)[1] IC50(app): 1.2 nM (enteropeptidase)[1] |
| In Vitro | Human enteropeptidase-IN-1 (compound 6b) has inhibitory activity against enteropeptidase with IC50(initial)* of 20 nM and IC50(app)** of 1.2 nM[1]. (*IC50(initial) refers to the inhibitory activity of human enteropeptidase after 6 min of incubation with the enzyme, substrate, and compound. **IC50(app) refers to the apparent IC50 value after 120 min of incubation with the enzyme, substrate, and compound.) |
| References |
| Molecular Formula | C20H18N4O7 |
|---|---|
| Molecular Weight | 426.38 |