LANA-DNA-IN-1

Modify Date: 2023-02-06 21:22:25

LANA-DNA-IN-1 structure	Common Name	LANA-DNA-IN-1
	CAS Number	2512847-06-0	Molecular Weight	330.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₄N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LANA-DNA-IN-1

LANA-DNA-IN-1 is a potent LANA-DNA inhibitor. LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC50 values of 8 μM, 9μM and 8μM. LANA-DNA-IN-1shows against wild-type LANA with IC50 value of 53 μM. LANA-DNA-IN-1 can be used for the research of infection[1].

Name	LANA-DNA-IN-1

Description	LANA-DNA-IN-1 is a potent LANA-DNA inhibitor. LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC50 values of 8 μM, 9μM and 8μM. LANA-DNA-IN-1shows against wild-type LANA with IC50 value of 53 μM. LANA-DNA-IN-1 can be used for the research of infection[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	IC50: 8 μM (LBS2); 9μM LBS1); 8 μM (LBS3); 53 μM (wild-type LANA)[1]
In Vitro	LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC50 values of 8 μM, 9μM and 8μM in FP Assay[1]. LANA-DNA-IN-1 has potent LANA-LBS1-inhibitory with an IC50 values of 53 μM[1]. LANA-DNA-IN-1 (31.25, 62.5, 125 and 250 μM) has potent against wild-type LANA CTD and the oligomerization-deficient LANA DBD mutant[1].
References	[1]. Philine Kirsch, et al. Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections. Eur J Med Chem. 2020 Sep 15;202:112525

Molecular Formula	C₁₉H₁₄N₄O₂
Molecular Weight	330.34

LANA-DNA-IN-1

Use of LANA-DNA-IN-1

Names

LANA-DNA-IN-1 Biological Activity

Chemical & Physical Properties