(3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate

Modify Date: 2025-08-21 18:30:35

(3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate structure	Common Name	(3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate
	CAS Number	870640-64-5	Molecular Weight	349.508
	Density	1.0±0.1 g/cm3	Boiling Point	426.3±35.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₃₅NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	211.6±25.9 °C

Use of (3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate

Monomethyl auristatin E intermediate-13 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Name	2-Methyl-2-propanyl (3R,4S,5S)-4-[benzyl(methyl)amino]-3-methoxy-5-methylheptanoate
Synonym	More Synonyms

Description	Monomethyl auristatin E intermediate-13 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.

Density	1.0±0.1 g/cm3
Boiling Point	426.3±35.0 °C at 760 mmHg
Molecular Formula	C₂₁H₃₅NO₃
Molecular Weight	349.508
Flash Point	211.6±25.9 °C
Exact Mass	349.261688
LogP	4.77
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.492
InChIKey	FJVJLCHQFIDUCO-HQRMLTQVSA-N
SMILES	CCC(C)C(C(CC(=O)OC(C)(C)C)OC)N(C)Cc1ccccc1

Heptanoic acid, 3-methoxy-5-methyl-4-[methyl(phenylmethyl)amino]-, 1,1-dimethylethyl ester, (3R,4S,5S)-

2-Methyl-2-propanyl (3R,4S,5S)-4-[benzyl(methyl)amino]-3-methoxy-5-methylheptanoate

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(3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate

Use of (3R,4S,5S)-tert-butyl 4-(benzyl(methyl)amino)-3-methoxy-5-methylheptanoate

Names

Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.