THP-PEG10-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-Boc-piperazine-C3-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-N-piperazine-C3-COOH can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].
Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Amino-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC50s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively[1].
Bromo-PEG4-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Benzyl-PEG9-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG4-CH2-aldehyde is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for the treatment of one or more diseases (extracted from patent WO2021170109A1) [1].
Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]<
Boc-N-amido-PEG4-C3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(Azido-PEG3)-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Dde Biotin-PEG4-TAMRA-PEG4 Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biotin-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Thiol-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
THP-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pyrene-amido-PEG4-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].