297162-48-2

297162-48-2 structure
297162-48-2 structure
  • Name: Br-PEG6-CH2COOtBu
  • Chemical Name: Br-PEG6-CH2COOtBu
  • CAS Number: 297162-48-2
  • Molecular Formula: C18H35BrO8
  • Molecular Weight: 459.37
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2022-04-27 20:08:46
  • Modify Date: 2024-01-09 20:06:25
  • Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Br-PEG6-CH2COOtBu
Description Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula C18H35BrO8
Molecular Weight 459.37