Bromo-PEG4-bromide structure
|
Common Name | Bromo-PEG4-bromide | ||
|---|---|---|---|---|
| CAS Number | 57602-02-5 | Molecular Weight | 364.071 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 373.2±32.0 °C at 760 mmHg | |
| Molecular Formula | C10H20Br2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 152.9±23.6 °C | |
Use of Bromo-PEG4-bromideBromo-PEG4-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
| Name | 1,14-Dibromo-3,6,9,12-tetraoxatetradecane |
|---|---|
| Synonym | More Synonyms |
| Description | Bromo-PEG4-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 373.2±32.0 °C at 760 mmHg |
| Molecular Formula | C10H20Br2O4 |
| Molecular Weight | 364.071 |
| Flash Point | 152.9±23.6 °C |
| Exact Mass | 361.972809 |
| PSA | 36.92000 |
| LogP | 0.80 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.489 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2909199090 |
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~86%
Bromo-PEG4-bromide CAS#:57602-02-5 |
| Literature: Biron, Eric; Otis, Francois; Meillon, Jean-Christophe; Robitaille, Martin; Lamothe, Julie; Van Hove, Patrick; Cormier, Marie-Eve; Voyer, Normand Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 6 p. 1279 - 1290 |
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Bromo-PEG4-bromide CAS#:57602-02-5 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 3 p. 557 - 560 Steroids, , vol. 71, # 10 p. 911 - 921 |
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Bromo-PEG4-bromide CAS#:57602-02-5 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 2 p. 636 - 643 |
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Bromo-PEG4-bromide CAS#:57602-02-5 |
| Literature: Canadian Journal of Chemistry, , vol. 66, p. 1097 - 1108 |
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Bromo-PEG4-bromide CAS#:57602-02-5 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 2 p. 636 - 643 |
| HS Code | 2909199090 |
|---|---|
| Summary | 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
| 3,6,9,12-Tetraoxatetradecane, 1,14-dibromo- |
| 1,14-Dibromo-3,6,9,12-tetraoxatetradecane |
| 1,2-bis[2-(2-bromoethoxy)ethoxy]ethane |