Bromo-PEG4-azide

Modify Date: 2024-01-09 13:51:32

Bromo-PEG4-azide Structure
Bromo-PEG4-azide structure
Common Name Bromo-PEG4-azide
CAS Number 1951439-37-4 Molecular Weight 326.19
Density N/A Boiling Point N/A
Molecular Formula C10H20BrN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG4-azide


Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG4-azide

 Bromo-PEG4-azide Biological Activity

Description Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H20BrN3O4
Molecular Weight 326.19
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