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1393330-38-5

1393330-38-5 structure
1393330-38-5 structure
  • Name: Bromo-PEG4-acid
  • Chemical Name: 1-Bromo-3,6,9,12-tetraoxapentadecan-15-oic acid
  • CAS Number: 1393330-38-5
  • Molecular Formula: C11H21BrO6
  • Molecular Weight: 329.185
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-11 04:21:32
  • Modify Date: 2024-02-03 17:45:19
  • Bromo-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-Bromo-3,6,9,12-tetraoxapentadecan-15-oic acid
Synonyms 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-
1-Bromo-3,6,9,12-tetraoxapentadecan-15-oic acid
MFCD22574799
Description Bromo-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.4±0.1 g/cm3
Boiling Point 426.9±40.0 °C at 760 mmHg
Molecular Formula C11H21BrO6
Molecular Weight 329.185
Flash Point 212.0±27.3 °C
Exact Mass 328.052155
LogP -0.37
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.481
Hazard Codes Xi