m-PEG4-azide structure
|
Common Name | m-PEG4-azide | ||
|---|---|---|---|---|
| CAS Number | 606130-90-9 | Molecular Weight | 233.26500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H19N3O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of m-PEG4-azidem-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
| Name | 1-azido-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane |
|---|---|
| Synonym | More Synonyms |
| Description | m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C9H19N3O4 |
|---|---|
| Molecular Weight | 233.26500 |
| Exact Mass | 233.13800 |
| PSA | 86.67000 |
| LogP | 0.44566 |
| Index of Refraction | 1.4500 to 1.4540 |
| Storage condition | 2-8°C |
|
~%
m-PEG4-azide CAS#:606130-90-9 |
| Literature: Li, Guangtao; Bhosale, Sheshanath V.; Wang, Tianyu; Hackbarth, Steffen; Roeder, Beate; Siggel, Ulrich; Fuhrhop, Juergen-Hinrich Journal of the American Chemical Society, 2003 , vol. 125, # 35 p. 10693 - 10702 |
|
~97%
m-PEG4-azide CAS#:606130-90-9 |
| Literature: Kitto, Heather J.; Schwartz, Erik; Nijemeisland, Marlies; Koepf, Matthieu; Cornelissen, Jeroen J. L. M.; Rowan, Alan E.; Nolte, Roeland J. M. Journal of Materials Chemistry, 2008 , vol. 18, # 46 p. 5615 - 5624 |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
| AmbotzPEG1690 |
| Me(OCH2CH2)4N3 |
| O-(2-Azidoethyl)-O inverted exclamation marka-methyl-triethylene glycol |
| MeO-PEG4-Azide |
| 1-azido-11-methoxy-3,6,9-trioxaundecane |
| 1-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-2-methoxyethane |
| m-dPEG.(TM).4-azide |
| 13-Azido-2,5,8,11-tetraoxatridecane |