m-PEG4-(CH2)3-methyl ester

Modify Date: 2024-01-12 19:17:13

m-PEG4-(CH2)3-methyl ester Structure
m-PEG4-(CH2)3-methyl ester structure
Common Name m-PEG4-(CH2)3-methyl ester
CAS Number 1920109-55-2 Molecular Weight 264.32
Density N/A Boiling Point N/A
Molecular Formula C12H24O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-(CH2)3-methyl ester


m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG4-CH2-methyl ester

 m-PEG4-(CH2)3-methyl ester Biological Activity

Description m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C12H24O6
Molecular Weight 264.32
Storage condition 2-8°C