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1872433-63-0

1872433-63-0 structure
1872433-63-0 structure
  • Name: Propargyl-PEG4-(CH2)3-methyl ester
  • Chemical Name: Propargyl-PEG4-CH2-methyl ester
  • CAS Number: 1872433-63-0
  • Molecular Formula: C14H24O6
  • Molecular Weight: 288.34
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:35:03
  • Modify Date: 2024-01-17 18:54:11
  • Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG4-CH2-methyl ester
Synonyms MFCD29079394
Description Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H24O6
Molecular Weight 288.34