Propargyl-PEG4-(CH2)3-methyl ester

Modify Date: 2024-01-17 18:54:11

Propargyl-PEG4-(CH2)3-methyl ester Structure
Propargyl-PEG4-(CH2)3-methyl ester structure
Common Name Propargyl-PEG4-(CH2)3-methyl ester
CAS Number 1872433-63-0 Molecular Weight 288.34
Density N/A Boiling Point N/A
Molecular Formula C14H24O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG4-(CH2)3-methyl ester


Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG4-CH2-methyl ester
Synonym More Synonyms

 Propargyl-PEG4-(CH2)3-methyl ester Biological Activity

Description Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H24O6
Molecular Weight 288.34

 Synonyms

MFCD29079394