Propargyl-PEG4-CH2CH2-Boc

Modify Date: 2024-01-31 09:15:01

Propargyl-PEG4-CH2CH2-Boc Structure
Propargyl-PEG4-CH2CH2-Boc structure
Common Name Propargyl-PEG4-CH2CH2-Boc
CAS Number 1245823-50-0 Molecular Weight 360.443
Density 1.0±0.1 g/cm3 Boiling Point 420.6±40.0 °C at 760 mmHg
Molecular Formula C18H32O7 Melting Point N/A
MSDS N/A Flash Point 179.0±27.4 °C

 Use of Propargyl-PEG4-CH2CH2-Boc


Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].

 Names

Name 2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
Synonym More Synonyms

 Propargyl-PEG4-CH2CH2-Boc Biological Activity

Description Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 420.6±40.0 °C at 760 mmHg
Molecular Formula C18H32O7
Molecular Weight 360.443
Flash Point 179.0±27.4 °C
Exact Mass 360.214813
LogP 0.53
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.456

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD22201534
2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
4,7,10,13,16-Pentaoxanonadec-18-yn-1-oic acid, 1,1-dimethylethyl ester