1920109-55-2

1920109-55-2 structure

Name: m-PEG4-(CH2)3-methyl ester
Chemical Name: m-PEG4-CH2-methyl ester
CAS Number: 1920109-55-2
Molecular Formula: C₁₂H₂₄O₆
Molecular Weight: 264.32
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-08 10:55:09
Modify Date: 2024-01-12 19:17:13
m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG4-CH2-methyl ester

Description	m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.