m-PEG4-SH

Modify Date: 2024-01-28 08:27:30

m-PEG4-SH Structure
m-PEG4-SH structure
Common Name m-PEG4-SH
CAS Number 52190-55-3 Molecular Weight 224.31800
Density 1.035 Boiling Point N/A
Molecular Formula C9H20O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-SH


m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol
Synonym More Synonyms

 m-PEG4-SH Biological Activity

Description m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.035
Molecular Formula C9H20O4S
Molecular Weight 224.31800
Exact Mass 224.10800
PSA 75.72000
LogP 0.61240
Storage condition 2-8°C

 Synonyms

3,6,9,12-Tetraoxatridecane-1-thiol
2,5,8,11-TETRAOXATRIDECANE-13-THIOL