m-PEG4-SH

Modify Date: 2026-08-06 10:52:25

m-PEG4-SH Structure
m-PEG4-SH structure
Common Name m-PEG4-SH
CAS Number 52190-55-3 Molecular Weight 224.31800
Density 1.035 Boiling Point N/A
Molecular Formula C9H20O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-SH


m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Summary: 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol (common name: m-PEG4-SH, CAS number: 52190-55-3) is a chemical with a molecular formula of C9H20O4S and a molecular weight of 224.31800. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol
Synonym More Synonyms

 m-PEG4-SH Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.035
Molecular Formula C9H20O4S
Molecular Weight 224.31800
Exact Mass 224.10800
PSA 75.72000
LogP 0.61240
InChIKey VXEBAWYHFQRROQ-UHFFFAOYSA-N
SMILES COCCOCCOCCOCCS
Storage condition 2-8°C

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

3,6,9,12-Tetraoxatridecane-1-thiol
2,5,8,11-TETRAOXATRIDECANE-13-THIOL

 m-PEG4-SH | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the storage conditions for 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: Storage conditions for 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol: 2-8°C.
Q: What is the English name of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: The English name of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol.
Q: What is the InChIKey of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: InChIKey of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is VXEBAWYHFQRROQ-UHFFFAOYSA-N.
Q: What is the SMILES notation of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: SMILES notation of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is COCCOCCOCCOCCS.
Q: What is the CAS number of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: CAS number of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is 52190-55-3.
Q: What English synonyms does 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol have?
A: English synonyms of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol: 3,6,9,12-Tetraoxatridecane-1-thiol, 2,5,8,11-TETRAOXATRIDECANE-13-THIOL.
Q: What is the molecular weight of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: Molecular weight of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is 224.31800.
Q: What is the molecular formula of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: Molecular formula of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is C9H20O4S.
Q: What are the uses of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: Main uses of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol: m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Q: What is the LogP of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol?
A: LogP of 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol is 0.61240.

 m-PEG4-SHfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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