Bromo-PEG4-CH2CO2tBu

Modify Date: 2024-01-11 15:59:30

Bromo-PEG4-CH2CO2tBu Structure
Bromo-PEG4-CH2CO2tBu structure
Common Name Bromo-PEG4-CH2CO2tBu
CAS Number 1807505-29-8 Molecular Weight 371.26
Density N/A Boiling Point N/A
Molecular Formula C14H27BrO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG4-CH2CO2tBu


Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Br-PEG4-CH2-Boc

 Bromo-PEG4-CH2CO2tBu Biological Activity

Description Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

 Chemical & Physical Properties

Molecular Formula C14H27BrO6
Molecular Weight 371.26
Storage condition -20°C
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