Bromo-PEG4-CH2CO2tBu

Names

[ CAS No. ]:
1807505-29-8

[ Name ]:
Bromo-PEG4-CH2CO2tBu

Biological Activity

[Description]:

Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₇BrO₆

[ Molecular Weight ]:
371.26

[ Storage condition ]:
-20°C

Related Compounds

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