2100306-54-3

2100306-54-3 structure

Name: Ald-CH2-PEG4-CH2CO2tBu
Chemical Name: Ald-CH2-PEG3-CH2-Boc
CAS Number: 2100306-54-3
Molecular Formula: C₁₄H₂₆O₇
Molecular Weight: 306.35
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-10 12:54:06
Modify Date: 2024-01-10 17:41:19
Ald-CH2-PEG3-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of SGK3 kinase PROTAC degrader[1].

Name	Ald-CH2-PEG3-CH2-Boc

Description	Ald-CH2-PEG3-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of SGK3 kinase PROTAC degrader[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.