2107273-28-7

2107273-28-7 structure

2107273-28-7 structure

Name: N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5
Chemical Name: N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5
CAS Number: 2107273-28-7
Molecular Formula: C₄₅H₆₀ClN₃O₁₀
Molecular Weight: 838.43
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:53:16
Modify Date: 2024-01-10 18:11:25
N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5

Description	N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₄₅H₆₀ClN₃O₁₀
Molecular Weight	838.43

Hazard Codes	Xi