Leucokinin I is a peptide that stimulates contraction of the anterior midgut and hindgut muscles involved in feeding in Rhodnius prolixus but not absorption in the anterior midgut[1].
Cycloshizukaol A is a symmetrical cyclic lindenane dimer with C2 symmetry. Cycloshizukaol A can be isolated from the root of Chloranthus serratus[1].
α-Latrotoxin, a potent neurotoxin from black widow spider venom, triggers synaptic vesicle exocytosis from presynaptic nerve terminals[1].
Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects[1]. Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of drug-drug interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones[2].
Iotalamic acid-d3 is the deuterium labeled Iotalamic acid[1].
CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.
Ethylbenzene-2,3,4,5,6-d5 is the deuterium labeled Ethylbenzene[1].
Hydroxysaikosaponin C is a natural product that can be isolated from the root of Bupleurum falcatum[1].
Rehmapicroside is an ionone glycoside isolated from rhizomes of Rehmannia glutinosa[1].
Fmoc-Gly-Bt is a Glycine (HY-Y0966) derivative[1].
GsMTx4 is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology[1]. GsMTx4 significantly attenuates bladder hyperactivity[2].
Amcasertib is an orally administered investigational agent designed to inhibit cancer stem cell pathways, including Nanog, by targeting stemness kinases.
O-Benzyl-D-serine is a serine derivative[1].
SDKPDMAEIEKFDKSK is a peptide derived from thymosin β4 (Tβ4)[1].
Uredepa is an insect chemosterilant. Uredepa can be used for the research of various biochemical studies[1].
Alisol C 23-acetate, a natural product extracted from Alisma orientale, can significantly and strongly inhibit DTH response after oral administration.
N-tert-Butoxycarbonyl-D-tyrosine methyl ester is a tyrosine derivative[1].
Cys(NPys)-D{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-NH2 is a cell-penetrating polypeptide composed of nine arginines and cysteines, used to carry therapeutic agent into the cell[1].
Mogroside VI, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1].
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
DL-Aspartic acid magnesium salt tetrahydrate is an aspartic acid derivative[1].
SRC-1 NR box peptide is a biological active peptide. (This peptide is a 14-amino acid fragment from the steroid receptor cofactor SRC-1 NR II.)
NSC305787 hydrochloride is an inhibitor of ezrin with a Kd of 5.85 μM, inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM, has antitumor activity.
[D-Val22, Phe33] Big Endothelin-1 (16-38), human is a polypeptide.
Chavicol β-D-glucoside is a phenylpropanoid heteroside. Chavicol β-D-glucoside can be isolated from subspecies of Cedronella canariensis[1].
Parishin is a phenolic glucoside isolated from Gastrodia elata. Parishin exhibits antiaging effects and extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway[1].
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu2+ in biological systems with λex/em=495/516 nm[1][2].
Lansoprazole sulfone N-oxide-d4 is the deuterium labeled Lansoprazole sulfone N-oxide[1].
Sodium 2-Methylpropionate-1-13C is the 13C labeled Sodium 2-Methylpropionate[1].