QM295

Modify Date: 2025-09-21 09:57:59

QM295 Structure
QM295 structure
Common Name QM295
CAS Number 1241046-32-1 Molecular Weight 295.29
Density N/A Boiling Point N/A
Molecular Formula C17H13NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of QM295


QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress[1].

 Names

Name QM295

 QM295 Biological Activity

Description QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress[1].
Related Catalog
In Vitro QM295(25 μM,50 μM)在动力学测定中抑制 AUR 荧光的发展,IC50 值为 1.9 μM[1]。
In Vivo QM295 (50 μM, 30 min) 在体内积累了迁移率较低的 ERO1α形式[1]。
References

[1]. Jaime D Blais, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003.  

 Chemical & Physical Properties

Molecular Formula C17H13NO4
Molecular Weight 295.29
InChIKey LRCZCFNUNZQGGK-LCYFTJDESA-N
SMILES COc1cc(C=C2C(=O)ON=C2c2ccccc2)ccc1O
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