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1241046-32-1

1241046-32-1 structure
1241046-32-1 structure
  • Name: QM295
  • Chemical Name: QM295
  • CAS Number: 1241046-32-1
  • Molecular Formula: C17H13NO4
  • Molecular Weight: 295.29
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2023-01-24 20:12:26
  • Modify Date: 2024-01-15 05:33:41
  • QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress[1].

Name QM295
Description QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress[1].
Related Catalog
In Vitro QM295(25 μM,50 μM)在动力学测定中抑制 AUR 荧光的发展,IC50 值为 1.9 μM[1]。
In Vivo QM295 (50 μM, 30 min) 在体内积累了迁移率较低的 ERO1α形式[1]。
References

[1]. Jaime D Blais, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003.  

Molecular Formula C17H13NO4
Molecular Weight 295.29
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