Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene

Modify Date: 2024-01-12 18:05:26

Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene Structure
Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene structure
Common Name Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene
CAS Number 16763-48-7 Molecular Weight 362.42
Density N/A Boiling Point N/A
Molecular Formula C20H26O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene


(19R)-13-Deoxy-19-hydroxyenmein is the parent compound of enmein-type diterpenoid analogs. (19R)-13-Deoxy-19-hydroxyenmein has anti-proliferative activities with IC50 values of 0.41, 0.85, 0.43, 1.89 μM against human cancer cell lines K562, MGC-803, CaEs-17, and Bel-7402, respectively[1].

 Names

Name Enmein, 13-deoxy-19-hydroxy-, (19R)-

  Biological Activity

Description (19R)-13-Deoxy-19-hydroxyenmein is the parent compound of enmein-type diterpenoid analogs. (19R)-13-Deoxy-19-hydroxyenmein has anti-proliferative activities with IC50 values of 0.41, 0.85, 0.43, 1.89 μM against human cancer cell lines K562, MGC-803, CaEs-17, and Bel-7402, respectively[1].
Related Catalog
References

[1]. Dahong Li, et al. Enmein-type diterpenoid analogs from natural kaurene-type oridonin: Synthesis and their antitumor biological evaluation. European Journal of Medicinal Chemistry. 2013, 64.

 Chemical & Physical Properties

Molecular Formula C20H26O6
Molecular Weight 362.42

 Safety Information

Hazard Codes Xi
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