Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene

Names

[ Name ]:
Ent-6beta,14alpha-dihydroxy-1,7-epoxy-7,15-dioxo-6,20-hemiketal-6,7-seco-16-kaurene

Biological Activity

[Description]:

(19R)-13-Deoxy-19-hydroxyenmein is the parent compound of enmein-type diterpenoid analogs. (19R)-13-Deoxy-19-hydroxyenmein has anti-proliferative activities with IC50 values of 0.41, 0.85, 0.43, 1.89 μM against human cancer cell lines K562, MGC-803, CaEs-17, and Bel-7402, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Dahong Li, et al. Enmein-type diterpenoid analogs from natural kaurene-type oridonin: Synthesis and their antitumor biological evaluation. European Journal of Medicinal Chemistry. 2013, 64.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₆O₆

[ Molecular Weight ]:
362.42

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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