Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
Lysozyme from chicken egg white is a bactericidal enzyme present in chicken eggs, and it lyses gram-positive bacteria.
Nociceptin, a heptadecapeptide, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic.
Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.
Angiogenin (108-122) is an angiogenin peptide.
[D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin. Sequence: Tyr-D-Ala-Gly-Phe-Leu.
HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.
Kinetensin is a neurotensin-like peptide isolated from pepsin-treated human plasma.
α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.
ACTH (22-39) is an adrenocorticotropic hormone (ACTH) fragment. ACTH (22-39) is the 22-39 sequence of ACTH.
Senktide is a tachykinin NK3 receptor agonist.
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
GRGDSPC, a 7-amino acid peptide, is a thiolated cell adhesion peptide.
Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.
740 Y-P (PDGFR 740Y-P) is a potent and cell permeable PI3K activator.
PA (224-233), Influenza is a 10-aa peptide, a fragment of polymerase 2 protein in influenza A virus.
Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
Neuropeptide W-23(human), the active form of Neuropeptide W, is an endogenous ligand for NPBW1 and NPBW2.
Endomorphin 2, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28.
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. Sequence: Cyclo(Ala-Asp-Phe-Lys-Arg).
Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors (NTR).
CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA substrate.
Pristinamycin IA is a cyclo-peptidic macrolactone antibiotic belonging to the streptogramin family, a substrate for the P-glycoprotein.In vitro: Pristinamycin IA specifically inhibits the efflux of the P-glycoprotein substrate [3H]vinblastine, thus increasing the cellular accumulation of the drug. Pristinamycin IA also reduces by 70% the basolateral to apical secretion of [3H]vinblastine across Caco-2 cell monolayers. The cellular accumulation of [14C]pristinamycin IA is very low and is increased by P-glycoprotein inhibitors (verapamil, chlorpromazine and reserpine). The basolateral to apical transport of [14C]pristinamycin IA is 100-fold higher than apical to basolateral passage. [1]
QL9 (QLSPFPFDL) is a high-affinity alloantigen for the 2C T cell receptor (TCR).
Angiotensin (1-7) inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC50 of 0.65 μM.
D-JNKI-1 is a specific inhibitor of JNK, and strongly interferes with JNK activation.
Gastric Inhibitory Peptide (GIP), human is thought to act as an inhibitor of gastric functions.
Kisspeptin-10 is a potent endogenous agonist for GPR54, used as a vasoconstrictor and an angiogenesis inhibitor.
Exendin-4 acetate, a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.