756500-23-9

756500-23-9 structure

Name: Cyclo(-Arg-Ala-Asp-D-Phe-Lys) trifluoroacetate salt
Chemical Name: Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl)
CAS Number: 756500-23-9
Molecular Formula: C₂₈H₄₃N₉O₇
Molecular Weight: 617.69700
Catalog: Peptides
Create Date: 2018-04-18 23:06:04
Modify Date: 2024-01-01 20:52:05
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. Sequence: Cyclo(Ala-Asp-Phe-Lys-Arg).

Name	Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl)
Synonyms	Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl) cyclo (Arg-Ala-Asp-d-Phe-Lys) Cyclo(RADfK)

Description	Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. Sequence: Cyclo(Ala-Asp-Phe-Lys-Arg).
Related Catalog	Signaling Pathways >> Cytoskeleton >> Integrin Research Areas >> Others Peptides
Target	Integrin[1].
In Vitro	Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family[1].
References	[1]. Srivatsan A, et al. Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics withenhanced tumor-imaging and photosensitizing (PDT) efficacy. Mol Pharm. 2011 Aug 1;8(4):1186-1197.