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15958-92-6

15958-92-6 structure

15958-92-6 structure

Name: (Des-Arg9)-Bradykinin acetate salt
Chemical Name: [Des-Arg9]-Bradykinin
CAS Number: 15958-92-6
Molecular Formula: C₄₄H₆₁N₁₁O₁₀
Molecular Weight: 904.023
Catalog: Peptides
Create Date: 2018-12-04 18:18:52
Modify Date: 2025-08-21 09:44:04
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.

Name	[Des-Arg9]-Bradykinin
Synonyms	L-phenylalanine, N-[[(2S)-1-[(2S)-2-[[(1Z,2S)-2-[[(1E)-2-[[(1Z)-[(2S)-1-[[(2S)-1-[(2S)-2-amino-5-[(aminoiminomethyl)amino]-1-oxopentyl]-2-pyrrolidinyl]carbonyl]-2-pyrrolidinyl]hydroxymethylene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-phenylpropylidene]amino]-3-hydroxy-1-oxopropyl]-2-pyrrolidinyl]hydroxymethylene]-, (Z)- 1-8-Bradykinin des-arginine9-bradykinin bradykinin fragment 1-8 9-Des-Arg-bk [des-Arg(9)]-bradykinin 9-De-Arg-bradykinin L-Phenylalanine, N-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl- des-Arg9-bradykinin RPPGFSPF DABK N-(Diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine des-Arg9-BK Bradykinin[Des-Arg9]

Description	[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Bradykinin Receptor Research Areas >> Inflammation/Immunology Peptides
Target	Bradykinin (B1) receptor[1]
In Vitro	The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].
References	[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

Density	1.5±0.1 g/cm3
Molecular Formula	C₄₄H₆₁N₁₁O₁₀
Molecular Weight	904.023
Exact Mass	903.460266
PSA	322.78000
LogP	0.64
Index of Refraction	1.687
Storage condition	-20°C

58-82-2 structure

58-82-2

~%

74-79-3 structure

74-79-3

15958-92-6 structure

15958-92-6

Literature: Umetsu, H.; Ichishima, E. Phytochemistry (Elsevier), 1983 , vol. 22, # 2 p. 591 - 592

Precursor 1
58-82-2
DownStream 0

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