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23827-91-0

23827-91-0 structure
23827-91-0 structure
  • Name: [Des-Arg9]-Bradykinin acetate
  • Chemical Name: [Des-Arg9]-Bradykinin acetate
  • CAS Number: 23827-91-0
  • Molecular Formula: C46H65N11O12
  • Molecular Weight: 964.07
  • Catalog: Peptides
  • Create Date: 2018-11-18 13:41:09
  • Modify Date: 2024-01-09 13:10:41
  • [Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.

Name [Des-Arg9]-Bradykinin acetate
Description [Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.
Related Catalog
Target

Bradykinin B1 receptor[1]

In Vitro [Des-Arg9]-Bradykinin acetate is a Bradykinin(B1) receptor agonist. The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].
References

[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

Molecular Formula C46H65N11O12
Molecular Weight 964.07