59401-28-4

59401-28-4 structure
59401-28-4 structure
  • Name: Mating Factor α acetate salt
  • Chemical Name: α(1)-mating factor
  • CAS Number: 59401-28-4
  • Molecular Formula: C82H114N20O17S
  • Molecular Weight: 1683.97000
  • Catalog: Biochemical Peptide
  • Create Date: 2018-08-12 01:31:30
  • Modify Date: 2025-08-27 10:30:46
  • α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.

Name α(1)-mating factor
Synonyms alpha1-Mating Factor acetate salt
alpha1-MATING FACTOR
MFCD00133883
Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr
A1-Mating Factor acetate salt
WHWLQLKPGQPMY
α-Factor Mating Pheromone, yeast
Description α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.
Related Catalog
Target

Ste2p[1]

In Vitro α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells[1]. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35S-α-factor to haploid a cells, with Kd of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability[2].
References

[1]. Naider F, et al. The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides. 2004 Sep;25(9):1441-63.

[2]. Jenness DD, et al. Binding of alpha-factor pheromone to yeast a cells: chemical and genetic evidence for an alpha-factor receptor. Cell. 1983 Dec;35(2 Pt 1):521-9.

Density 1.338 g/cm3
Boiling Point 1995.8ºC at 760 mmHg
Molecular Formula C82H114N20O17S
Molecular Weight 1683.97000
Exact Mass 1682.84000
PSA 612.93000
LogP 6.31310
Index of Refraction 1.625
Storage condition −20°C
Water Solubility H2O: 1 mg/mL, clear, colorless | Soluble in water at 1mg/ml
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
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