Mating Factor α acetate salt

Modify Date: 2025-08-27 10:30:46

Mating Factor α acetate salt Structure
Mating Factor α acetate salt structure
Common Name Mating Factor α acetate salt
CAS Number 59401-28-4 Molecular Weight 1683.97000
Density 1.338 g/cm3 Boiling Point 1995.8ºC at 760 mmHg
Molecular Formula C82H114N20O17S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Mating Factor α acetate salt


α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.

 Names

Name α(1)-mating factor
Synonym More Synonyms

 Mating Factor α acetate salt Biological Activity

Description α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.
Related Catalog
Target

Ste2p[1]

In Vitro α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells[1]. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35S-α-factor to haploid a cells, with Kd of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability[2].
References

[1]. Naider F, et al. The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides. 2004 Sep;25(9):1441-63.

[2]. Jenness DD, et al. Binding of alpha-factor pheromone to yeast a cells: chemical and genetic evidence for an alpha-factor receptor. Cell. 1983 Dec;35(2 Pt 1):521-9.

 Chemical & Physical Properties

Density 1.338 g/cm3
Boiling Point 1995.8ºC at 760 mmHg
Molecular Formula C82H114N20O17S
Molecular Weight 1683.97000
Exact Mass 1682.84000
PSA 612.93000
LogP 6.31310
Index of Refraction 1.625
Storage condition −20°C
Water Solubility H2O: 1 mg/mL, clear, colorless | Soluble in water at 1mg/ml

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles2

More Articles
Synthesis of the mating factor of Saccharomyces cerevisiae and its truncated peptides : the structure-activity relationship.

Biochem. Biophys. Res. Commun. 78 , 534, (1977)

Gcn5p plays an important role in centromere kinetochore function in budding yeast.

Mol. Cancer Ther. 28 , 988-96, (2008)

We report that the histone acetyltransferase Gcn5p is involved in cell cycle progression, whereas its absence induces several mitotic defects, including inefficient nuclear division, chromosome loss, ...

 Synonyms

alpha1-Mating Factor acetate salt
alpha1-MATING FACTOR
MFCD00133883
Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr
A1-Mating Factor acetate salt
WHWLQLKPGQPMY
α-Factor Mating Pheromone, yeast
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