Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Gynosaponin I

Gynosaponin I (compound 1) is a natural product that can be found in Gynostemma pentaphyllum[1].

  • CAS Number: 1207861-69-5
  • MF: C42H72O12
  • MW: 769.01
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 851.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 468.5±34.3 °C

n-(2-cyanoethyl)glycine

N-(2-Cyanoethyl)glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 3088-42-4
  • MF: C5H8N2O2
  • MW: 128.12900
  • Catalog: Others
  • Density: 1.187g/cm3
  • Boiling Point: 343.1ºC at 760mmHg
  • Melting Point: 188-193 °C
  • Flash Point: 161.3ºC

RAD16-I hydrochloride

RAD16-I hydrochloride, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes[1]. RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs[2].

  • CAS Number: 2100275-49-6
  • MF: C66H113N29O25.xHCl
  • MW:
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nurr1 agonist 8

Nurr1 agonist 8 (compound 111) is a Nurr1 agonist with an EC50 value of 0.09 μM[1].

  • CAS Number: 360778-55-8
  • MF: C14H10Cl2O3
  • MW: 297.13300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hemoglobin

Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant[1].

  • CAS Number: 9008-02-0
  • MF: C13H10N2O2
  • MW: 226.2307
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 400.9±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.3±28.7 °C

3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester

3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester is a hederagenin-type saponin with antitumor and anti-inflammatory properties[1].

  • CAS Number: 128717-92-0
  • MF: C52H84O21
  • MW: 1045.21
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cochliodinol

Cochliodinol (compound 1) is a metabolite derived from the Apis mellifera ligustica. Cochliodinol has strong free radical scavenging activity of 2, 2-diphenyl-1-picrohydrazine (DPPH) (IC50=3.06 μg/mL)[1].

  • CAS Number: 11051-88-0
  • MF: C32H30N2O4
  • MW: 506.59
  • Catalog: Metabolic Disease
  • Density: 1.344g/cm3
  • Boiling Point: 790ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 431.6ºC

Caulophylline B

Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical[1].

  • CAS Number: 1359978-55-4
  • MF: C19H21NO5
  • MW: 343.374
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fluorescein di(β-D-galactopyranoside)

Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm).

  • CAS Number: 17817-20-8
  • MF: C32H32O15
  • MW: 656.58700
  • Catalog: Dye Reagents
  • Density: 1.74 g/cm3
  • Boiling Point: 974.8ºC at 760 mmHg
  • Melting Point: 200-203ºC (dec.)
  • Flash Point: 316.5ºC

Monomethyl auristatin E intermediate-5

Monomethyl auristatin E intermediate-5 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

  • CAS Number: 1822810-13-8
  • MF: C19H27NO5
  • MW: 349.42
  • Catalog: Cancer
  • Density: 1.100±0.06 g/cm3(Predicted)
  • Boiling Point: 464.4±35.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

9-methylanthracene-d12

9-Methylanthracene-d12 is the deuterium labeled 9-Methylanthracene[1].

  • CAS Number: 6406-97-9
  • MF: C15D12
  • MW: 204.33000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TGR5 Receptor Agonist 4

TGR5 Receptor Agonist 4 is an agonist of Bile Acid Receptor (TGR5), with EC50 for hTGR5 and mTGR5 of 2 nM and 3 nM, respectively. TGR5 Receptor Agonist plays important roles in hypoglycemic and weight loss[1].

  • CAS Number: 1872436-42-4
  • MF: C25H27ClN2O5
  • MW: 470.95
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-DL-Nva-OH

N-Carbobenzoxy-DL-norvaline is a valine derivative[1].

  • CAS Number: 21691-43-0
  • MF: C13H17NO4
  • MW: 251.278
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 439.4±38.0 °C at 760 mmHg
  • Melting Point: 88ºC
  • Flash Point: 219.6±26.8 °C

1,4-bUtanedithiol-d8

1,4-bUtanedithiol-d8 is the deuterium labeled 1,4-bUtanedithiol[1].

  • CAS Number: 1219805-46-5
  • MF: C4H10S2
  • MW: 122.252
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 196.3±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 74.6±14.7 °C

Linavonkibart

Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-Hydroxy-3,5,7,3',4',5'-hexamethoxyflavone

8-Hydroxy-3,5,7,3',4',5'-hexamethoxyflavone is a natural flavonoid compound[1].

  • CAS Number: 202846-95-5
  • MF: C21H22O9
  • MW: 418.39
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 630.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 220.8±25.0 °C

Sitakisogenin

53187-93-2

  • CAS Number: 53187-93-2
  • MF: C30H50O4
  • MW: 474.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(10E)-10-Pentadecenoic acid

10(E)-Pentadecenoic Acid (trans-10-Pentadecenoic acid) is a long-chain monounsaturated fatty acid containing 15 carbons[1].

  • CAS Number: 321744-58-5
  • MF: C15H28O2
  • MW: 240.38
  • Catalog: Metabolic Disease
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 321.9±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.9±14.4 °C

7ß,27-Dihydroxycholesterol-d6

7ß,27-Dihydroxycholesterol-d6 is deuterium labeled 7ß,27-Dihydroxycholesterol.

  • CAS Number: 2260669-26-7
  • MF: C27H40D6O3
  • MW: 424.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phenindione-d5

Phenindione D5 is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.

  • CAS Number: 70711-53-4
  • MF: C15H5D5O2
  • MW: 227.27000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Cystine

D-Cystine is the D-enantiomer of L-Cystine. D-Cystine inhibits L-aspartate-β-semialdehyde dehydrogenase (ASADH) from Escherichia coli[1].

  • CAS Number: 349-46-2
  • MF: C6H12N2O4S2
  • MW: 240.301
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 468.2±45.0 °C at 760 mmHg
  • Melting Point: 260ºC
  • Flash Point: 237.0±28.7 °C

G2-peptide

G2-Peptide is an peptide. G2-Peptide can be used for the research of various biochemical[1].

  • CAS Number: 361443-81-4
  • MF: C90H155N13O54
  • MW: 2283.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-ALPHA-(3-NITRO-2-PYRIDINESULFENYL)-N-IM-TOSYL-L-HISTIDINE

Nα-(3-Nitro-2-pyridinesulfenyl)-N-im-tosyl-L-histidine is a histidine derivative[1].

  • CAS Number: 108312-26-1
  • MF: C18H17N5O6S2
  • MW: 463.48700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fluridone

Fluridone is an inhibitor of abscisic acid (ABA) biosynthesis. Fluridone suppresses the expression of AchnFAR and TF genes and reduces the formation of primary alcohols[1].

  • CAS Number: 59756-60-4
  • MF: C19H14F3NO
  • MW: 329.316
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 444.4±45.0 °C at 760 mmHg
  • Melting Point: 154-155°C
  • Flash Point: 222.6±28.7 °C

1,3-Benzenediol, 5-(7-((2E)-3,7-dimethyl-2,6-octadienyl)-6-methoxy-2-b enzofuranyl)-

Mulberrofuran B can be isolated from the Ethanol extract of Morus alba. Mulberrofuran B has antioxidant activity[1].

  • CAS Number: 79295-49-1
  • MF: C25H28O4
  • MW: 392.48700
  • Catalog: Others
  • Density: 1.14g/cm3
  • Boiling Point: 579.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.1ºC

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 957780-56-2
  • MF: C31H38N2O8
  • MW: 566.642
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 760.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 413.7±32.9 °C

2-Acetyl-1H-pyrrole

2-Acetylpyrrole is a product of model browning systems, and has been isolated as a major flavour component of many foods[1]. 2-Acetylpyrrole has been used in the synthesis of 2-acetyl-1-pyrroline[2].

  • CAS Number: 1072-83-9
  • MF: C6H7NO
  • MW: 109.126
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 220.9±13.0 °C at 760 mmHg
  • Melting Point: 88-93 °C(lit.)
  • Flash Point: 92.4±27.3 °C

APC 366 TFA

APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].

  • CAS Number: 2421110-28-1
  • MF: C24H29F3N6O6
  • MW: 554.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secoisolariciresinol diglucoside

Secoisolariciresinol diglucoside is a plant lignan isolated from flaxseed, an antagonist of platelet activating factor-receptor, and used as an antioxidant.

  • CAS Number: 158932-33-3
  • MF: C32H46O16
  • MW: 686.698
  • Catalog: Cardiovascular Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 989.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 552.0±34.3 °C

ZINC00640089

ZINC00640089 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC)[1].

  • CAS Number: 667880-11-7
  • MF: C20H13F3N2O2
  • MW: 370.32
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A