Monomethyl auristatin E intermediate-5

Modify Date: 2025-09-20 16:39:03

Monomethyl auristatin E intermediate-5 structure	Common Name	Monomethyl auristatin E intermediate-5
	CAS Number	1822810-13-8	Molecular Weight	349.42
	Density	1.100±0.06 g/cm3(Predicted)	Boiling Point	464.4±35.0 °C(Predicted)
	Molecular Formula	C₁₉H₂₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Monomethyl auristatin E intermediate-5

Monomethyl auristatin E intermediate-5 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Name	tert-Butyl 4-(((benzyloxy)carbonyl)amino)-5-methyl-3-oxohexanoate

Description	Monomethyl auristatin E intermediate-5 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.

Density	1.100±0.06 g/cm3(Predicted)
Boiling Point	464.4±35.0 °C(Predicted)
Molecular Formula	C₁₉H₂₇NO₅
Molecular Weight	349.42

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Monomethyl auristatin E intermediate-5

Use of Monomethyl auristatin E intermediate-5

Names

Monomethyl auristatin E intermediate-5 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.