2421110-28-1

2421110-28-1 structure
2421110-28-1 structure
  • Name: APC 366 TFA
  • Chemical Name: APC 366 TFA
  • CAS Number: 2421110-28-1
  • Molecular Formula: C24H29F3N6O6
  • Molecular Weight: 554.52
  • Catalog: Research Areas Others
  • Create Date: 2021-09-11 23:14:44
  • Modify Date: 2024-01-08 18:17:33
  • APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].

Name APC 366 TFA
Description APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].
Related Catalog
Target

mast cell tryptase[1]

In Vivo APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1]. Animal Model: Male BALB/c mice (18–25 g)[1] Dosage: 5 mg/kg/0.1 ml Administration: S.c. Result: Reduced the eosinophil recruitment induced by PAR-2 activating peptide.
References

[1]. Matos NA, et al. Mast cell tryptase induces eosinophil recruitment in the pleural cavity of mice via proteinase-activated receptor 2. Inflammation. 2013;36(6):1260-1267.

Molecular Formula C24H29F3N6O6
Molecular Weight 554.52