APC 366 TFA

Modify Date: 2024-01-08 18:17:33

APC 366 TFA Structure
APC 366 TFA structure
Common Name APC 366 TFA
CAS Number 2421110-28-1 Molecular Weight 554.52
Density N/A Boiling Point N/A
Molecular Formula C24H29F3N6O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of APC 366 TFA


APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].

 Names

Name APC 366 TFA

 APC 366 TFA Biological Activity

Description APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].
Related Catalog
Target

mast cell tryptase[1]

In Vivo APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1]. Animal Model: Male BALB/c mice (18–25 g)[1] Dosage: 5 mg/kg/0.1 ml Administration: S.c. Result: Reduced the eosinophil recruitment induced by PAR-2 activating peptide.
References

[1]. Matos NA, et al. Mast cell tryptase induces eosinophil recruitment in the pleural cavity of mice via proteinase-activated receptor 2. Inflammation. 2013;36(6):1260-1267.

 Chemical & Physical Properties

Molecular Formula C24H29F3N6O6
Molecular Weight 554.52