APC 366

Modify Date: 2025-08-26 18:09:44

APC 366 structure	Common Name	APC 366
	CAS Number	158921-85-8	Molecular Weight	440.496
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₈N₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of APC 366

APC 366 is a selective inhibitor of mast cell tryptase (Ki=7.1 μM). APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma[1][2].

Name	APC 366
Synonym	More Synonyms

Description	APC 366 is a selective inhibitor of mast cell tryptase (Ki=7.1 μM). APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Inflammation/Immunology
References	[1]. Barrios VE, et al. Tryptase mediates hyperresponsiveness in isolated guinea pig bronchi. Life Sci. 1998;63(26):2295-2303. [2]. Krishna MT, et al. Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma. J Allergy Clin Immunol. 2001;107(6):1039-1045.

Description

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease

Research Areas >> Inflammation/Immunology

References

[1]. Barrios VE, et al. Tryptase mediates hyperresponsiveness in isolated guinea pig bronchi. Life Sci. 1998;63(26):2295-2303.

[2]. Krishna MT, et al. Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma. J Allergy Clin Immunol. 2001;107(6):1039-1045.

Density	1.5±0.1 g/cm3
Molecular Formula	C₂₂H₂₈N₆O₄
Molecular Weight	440.496
Exact Mass	440.217194
LogP	0.92
Index of Refraction	1.695

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N5-(Diaminomethylene)-N2-(1-hydroxy-2-naphthoyl)-L-ornithyl-L-prolinamide

N2-[(1-hydroxynaphthalen-2-yl)carbonyl]-L-arginyl-L-prolinamide

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: APC 366
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: APC 366
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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APC 366

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.