GSK 366

Modify Date: 2024-01-10 16:49:56

GSK 366 Structure
GSK 366 structure
Common Name GSK 366
CAS Number 1953157-39-5 Molecular Weight 361.78
Density N/A Boiling Point N/A
Molecular Formula C17H16ClN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK 366


GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO), respectively [1].

 Names

Name GSK 366

 GSK 366 Biological Activity

Description GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO), respectively [1].
Related Catalog
Target

IC50: 2.3 nM (human KMO), 0.7 nM (Pf-KMO)[1]

References

[1]. Hutchinson JP, et al. Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. Nat Commun. 2017 Jun 12;8:15827.

 Chemical & Physical Properties

Molecular Formula C17H16ClN3O4
Molecular Weight 361.78
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